psychiatric manifestations of corticosteroid therapy

Introduction Children and adolescents treated with corticosteroids (CS) may experience psychiatric side effects, including psychotic symptoms. These can occur at any time during treatment, withdrawal. There is evidence in the adult literature that higher doses of CS increase this risk. However, dose-response relationship not clearly identifiable. This probably a reflection complexity effects on central nervous system body. Objectives objective study to discuss manifestations secondary corticosteroid therapy Methods descriptive 10 children history somatic pathologies for which they were placed oral, nasal, or intravenous who course presented various manifestations. Results The majority studied male, i.e., 7 boys 3 girls, six either 60%, nasal corticosteroids; 20% corticosteroids, ., orally. noted represented by : depressive disorder 8 childrens Anxiety one child ADHD childrens. Conclusions A causal role development mental disorders has been widely discussed but results are controversial respect route administration, dose chronology disorders. Disclosure Interest None Declared